An Exhaustive Shape-Based Approach for Proteins' Secondary, Tertiary and Quaternary Structures Indexing, Retrieval and Docking
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Designing and analyzing the structure of Tat-BoNT/A(1-448) fusion protein: An in silico approach
Clostridium botulinum type A (BoNT/A) produces a neurotoxin recently found to be useful as an injectable drug for the treatment of abnormal muscle contractions. The catalytic domain of this toxin which is responsible for the main toxin activity is a zinc metalloprotease that inhibits the release of neurotransmitter mediators in neuromuscular junctions. A cell penetrating cationic peptide, Tat, ...
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